Drug pricing 

Remember:

"Pharma bro" Shkreli went to jail for securities fraud, not for hiking up drug prices

The drug is still crazy expensive

"Researchers and manufacturers face possible jail time β€” or execution β€” for fraudulent submissions to nation's drug agency"

nature.com/news/china-cracks-d

Any drug is promising in silico if your mathematical model is bad enough!

Drugs that are approved by the FDA based on limited evidence are rarely redeemed with better evidence after approval

bmj.com/content/357/bmj.j1680.