James Lloyd @jamespblloyd@scholar.social

I am overjoyed to share that my work on gene circuits in plants has been published in Nature Biotechnology:

Synthetic memory circuits for stable cell reprogramming in plants

https://www.nature.com/articles/s41587-022-01383-2

It is fantastic to see this wonderful work out:

CRISPRi-based circuits for genetic computation in plants

A new way to build gene circuits in plants. A wonderful example of how the Design-Build-Test-Learn cycle of synthetic biology works by the talented Adil Khan.

https://www.biorxiv.org/content/10.1101/2022.07.01.498372v1

If you could choose one extinct organism to study from the past, what would it be?

For me it would probably be the Last Eukaryotic Common Ancestor (LECA), to see what we were like before animals and plants diverged.

Or a land plant from ~500mya to see what early plants were really like and how similar to modern day mosses and liverworts they really are.

#Question #biology

When performing plant genetic engineering, we often have to choose between cell type/tissue specific expression or condition (chemical/stress) induced. 

With genetic circuits we can make a new system that combines the properties of both. Read more here:

https://www.biorxiv.org/content/10.1101/2022.02.11.480167v1.full

For anyone interesting in the debate around GMOs, I did write a blog post about it:

Genetically modified myths examined.

http://www.curiousmeerkat.co.uk/guest-blog/genetically-modified-myths-examined/

If people want a short and accessible article summarising genetic circuits in plants (including my recent work), please check out this prelight.

I am always happy to discuss value and limitations of genetic circuits in plants or genetic engineering in general.

https://prelights.biologists.com/highlights/synthetic-gene-circuits-in-plants/

Hi I am a researcher building genetic circuits in plants and interesting in an academic career. Here is a link to some of my work: https://www.biorxiv.org/content/10.1101/2022.02.11.480167v1.abstract

#introductions